Cancering and Proteomics
In fact, we misunderstand cancer by making it a noun. Instead of saying, “You know, my house has water”, we say, “My plumbing is leaking.” Instead of saying, “Somebody has cancer”, we should say, “They’re cancering.” The truth of the matter is we’re probably cancering all the time, and our body is checking it in various ways, so we’re not cancering out of control. Probably every house has a few leaky faucets, but it doesn’t matter much because there are processes that are mitigating that, by draining away the leaks. Cancer is probably something like that.
In order to understand what’s actually going on, we have to look at the level of the things that are actually happening, and that level is proteomics. Now that we can actually measure that conversation between the parts, then we’re going to start building up a model that’s a cause-and-effect model: This signal causes this to happen, that causes that to happen. Maybe we will not understand to the level of the molecular mechanism but we can have a kind of cause-and-effect picture of the process. More like we do in sociology or economics.
Whatever the treatment of cancer, or auto-immune disease, neurodegenerative disease or other system diseases will be like in the future, there won’t be a diagnosis step, or at least that’s not what will determine your treatment. Instead, what we’ll do is we’ll go in, we’ll measure you by imaging techniques, and taking it off of your blood, looking at the proteins, things like that, build a model of your state, have a model of how your state progresses, and we’ll do it more like global climate modeling